Patients with heart failure with mid-range ejection fraction: role of comorbidity

Abstract Funding Acknowledgements Type of funding sources: None. Patients with mid-range ejection fraction (HFmrEF) are still a ‘grey area’ for clinical practice. The aim this study was to investigate comorbidity, quality life and psychological status patients HFmrEF. Materials methods. One hundred four CHF (69 males 35 females, mean age 61.7 ± 9.6 years) were studied. defined according ESC Guidelines the diagnosis treatment acute chronic heart failure, 2016. Age-adjusted Charlson Comorbidity Index (ACCI) calculated. regarded as high at index ≥ 6 scores. Psychological state, cognitive functions, adherence estimated using MMPI, MMSE, SF-36 Health Status Survey, Four-Item Morisky Green Levine Medication Adherence Scale. Follow-up period 12 months. Results. Forty-six (44.2%) had HFmrEF, 58 (55.8%) - failure preserved (HFpEF). comorbidity did not differ depending on left ventricular (LV) (EF) (5.4 2.1 points HFmrEF 4.8 HFpEF, resp., p = 0.1). LV mass (LVMI) more in than HFpEF: 213.4 57.7 176.6 44.3 g/m2, 0.009. higher functional class HF (the Minute walk test 307.4 92.4 m 339.0 78.7 0.02). Twelve (11.5%) died during 12-month follow-up. Mortality LVEF differ. lower indicators physical scale: functioning (36.3 14.2 48.1 13.3 resp. 0.006) health scale (33.4 5.3 35.8 6.7 points, resp.,p 0.03) compared HFpEF. full both groups low (30%) profile depressive-hypochondriacal conditions, primitive maladaptive defense mechanisms Conclusion. characterized by severe course, frequency comparison which should be taken into account development interdisciplinary approach category patients.